What is the cause of Wolf Hirschhorn Syndrome?
Likewise, what are the symptoms of Wolf Hirschhorn Syndrome?
Wolf-Hirschhorn syndrome (WHS) is a genetic disorder that affects many parts of the body. The major features include a characteristic facial appearance, delayed growth and development, intellectual disability , low muscle tone ( hypotonia ), and seizures .
Keeping this in consideration, what is the treatment for Wolf Hirschhorn Syndrome?
There is no cure for Wolf-Hirschhorn syndrome, and every patient is unique, so treatment plans are tailored to manage the symptoms. Most plans will include: Physical or occupational therapy. Surgery to repair defects.
WHS is inherited in an autosomal dominant pattern. This means inheriting one 4p16. 3 microdeletion is enough for an individual to be affected and show signs of WHS. In approximately 55% of cases, the deletion occurs brand new (de novo) in an affected child.