What is the cause of Wolf Hirschhorn Syndrome?
Likewise, what are the symptoms of Wolf Hirschhorn Syndrome?
Wolf-Hirschhorn syndrome (WHS) is a genetic disorder that affects many parts of the body. The major features include a characteristic facial appearance, delayed growth and development, intellectual disability , low muscle tone ( hypotonia ), and seizures .
Similarly, what is the life expectancy of a person with Wolf Hirschhorn Syndrome? The long-term outlook ( prognosis ) for people with Wolf-Hirschhorn syndrome (WHS) depends on the specific features present and the severity of those features. The average life expectancy is unknown. Muscle weakness may increase the risk of having chest infections and ultimately may reduce the life expectancy.
Keeping this in consideration, what is the treatment for Wolf Hirschhorn Syndrome?
There is no cure for Wolf-Hirschhorn syndrome, and every patient is unique, so treatment plans are tailored to manage the symptoms. Most plans will include: Physical or occupational therapy. Surgery to repair defects.
Is Wolf Hirschhorn syndrome dominant or recessive?
WHS is inherited in an autosomal dominant pattern. This means inheriting one 4p16. 3 microdeletion is enough for an individual to be affected and show signs of WHS. In approximately 55% of cases, the deletion occurs brand new (de novo) in an affected child.