How does hyponatremia cause lithium toxicity?
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Likewise, how does sodium affect lithium levels?
Salt consumption can cause fluctuations in serum lithium levels. A sudden decrease in sodium intake (a component of salt) may result in higher serum lithium levels, while a sudden increase in sodium might prompt your lithium levels to fall. Caffeine might interact with serum lithium levels.
Likewise, what are the 3 main symptoms of lithium toxicity?
- diarrhea.
- vomiting.
- stomach pains.
- fatigue.
- tremors.
- uncontrollable movements.
- muscle weakness.
- drowsiness.
In this regard, can lithium toxicity cause diabetes insipidus?
Nephrogenic diabetes insipidus (NDI) is the most common renal side effect of lithium therapy [2,3]. (See "Lithium poisoning".) NEPHROGENIC DIABETES INSIPIDUS. Normally, water permeability of principal cells in the collecting tubule is regulated by antidiuretic hormone (ADH).
How does dehydration cause lithium toxicity?
Toxicity can also be caused by taking a slightly higher dose of lithium over time. It can also occur if you are dehydrated, or you take medicines that cause lithium to build up in your blood. A decreased intake of sodium (salt) can also lead to lithium toxicity.