Can Gilbert's syndrome cause anxiety?

Asked By: Guodong Dunkelau | Last Updated: 1st February, 2020
Category: medical health digestive disorders
4.8/5 (426 Views . 44 Votes)
Gilbert's syndrome and jaundice
Studies of people with Gilbert's syndrome also reveal they are particularly prone to vague symptoms such as extreme tiredness, headaches, dizziness and nausea, stomach and abdominal discomfort. They often experience anxiety symptoms and insomnia.

Click to see full answer


Keeping this in consideration, what medications should be avoided with Gilbert's syndrome?

Drugs that should be avoided, if possible, are:

  • Atazanavir and indinavir, used to treat HIV infection.
  • Gemfibrozil, for lowering cholesterol.
  • Statins, also used for reducing cholesterol, when taken with gemfibrozil.
  • Irinotecan, used to treat advanced bowel cancer.
  • Nilotinib, for the treatment of some blood cancers.

Subsequently, question is, can Gilbert's syndrome cause stomach pains? Symptoms of Gilbert's syndrome As Gilbert's syndrome usually only causes a slight increase in bilirubin levels, the yellowing of jaundice is often mild. Some people also report other problems during episodes of jaundice, including: tummy (abdominal) pain. feeling very tired (fatigue)

Correspondingly, can you drink if you have Gilbert's syndrome?

Some people with Gilbert's syndrome also find that drinking alcohol makes their symptoms worse. For some people, even one or two drinks can make them feel sick shortly after. Alcohol can temporarily raise bilirubin levels in people with Gilbert's syndrome.

Can stress cause Gilbert's?

Gilbert syndrome is associated with fluctuating levels of bilirubin in the blood (hyperbilirubinemia). Bilirubin levels may increase with stress, strain, dehydration, fasting, infection or exposure to cold. In many individuals, jaundice is only evident when one of these triggers raises the bilirubin levels.

35 Related Question Answers Found

What foods should you avoid with Gilbert's syndrome?

Most animal products (meat, eggs, dairy) should be eaten sparingly, as should aged or fermented products such as bread, beer, cheese, wine, cured meats, and tobacco. Aspirin should be avoided altogether. Including plenty of fresh fruits and vegetables will help during this period of healing and repair.

Can I give blood if I have Gilbert's syndrome?

Must not donate if:
Gilbert's syndrome is an inherited defect in bilirubin metabolism. It is harmless but can cause jaundice (yellowing of the whites of the eyes). Blood banks are unlikely to use blood that appears jaundiced. This means any visibly jaundiced donation is likely to be wasted.

Does Gilbert's syndrome make you tired?

The most common symptom of Gilbert's syndrome is jaundice. Some people with the condition also experience fatigue (tiredness), dizziness, or discomfort in the abdomen (belly). People with Gilbert's syndrome typically experience symptoms in certain situations in which levels of bilirubin in the blood rise.

What triggers Gilbert syndrome?

An abnormal gene you inherit from your parents causes Gilbert's syndrome. The gene normally controls an enzyme that helps break down bilirubin in your liver. When you have an ineffective gene, your blood contains excess amounts of bilirubin because your body doesn't produce enough of the enzyme.

How can I lower my bilirubin naturally?


Quick tips
  1. Drink at least eight glasses of fluids per day.
  2. Consider adding milk thistle to your routine.
  3. Opt for fruits like papaya and mango, which are rich in digestive enzymes.
  4. Eat at least 2 1/2 cups of veggies and 2 cups of fruit per day.
  5. Look for high-fiber foods, such as oatmeal, berries, and almonds.

Can Gilbert's syndrome cause cancer?

When it is finally discovered, most patients carrying this mutation require no treatment. But there is more reason for feeling relieved. Surprisingly, researchers found evidence that mildly elevated bilirubin levels reduce the risk of developing cancer and cardiovascular diseases.

Is Gilbert's syndrome an autoimmune disease?

Gilbert syndrome is a mild liver disorder that impairs the body's ability to process bilirubin, a substance made when old red blood cells are broken down. Gilbert syndrome is caused by mutations in the UGT1A1 gene and inheritance is autosomal recessive .

Does fasting increase bilirubin?

RESULTS: We found a statistically significant increase in total serum bilirubin levels in fasting males as compared with non-fasting males. The fasting time correlated positively with increased bilirubin levels. We found no correlation between fasting and bilirubin levels in clinically normal females.

Can you take paracetamol with Gilbert's syndrome?

Statins are only partly metabolised by the UGT so they are safe in most people with Gilbert's syndrome. Although paracetamol is also partly metabolised by UGT, some people with Gilbert's syndrome do remove it more slowly from the body, so it may be better to use another pain killer when necessary.

What does Gilbert syndrome do?


Gilbert syndrome is a relatively mild condition characterized by periods of elevated levels of a toxic substance called bilirubin in the blood (hyperbilirubinemia). Bilirubin, which has an orange-yellow tint, is produced when red blood cells are broken down.

How high is bilirubin in Gilbert's syndrome?

People with GS predominantly have elevated unconjugated bilirubin, while conjugated bilirubin is usually within the normal range and is less than 20% of the total. Levels of bilirubin in GS patients are reported to be from 20 μM to 90 μM (1.2 to 5.3 mg/dl) compared to the normal amount of < 20 μM.

What foods increase bilirubin levels?

Fresh fruits and vegetables
  • whole cranberries, blueberries, and grapes.
  • citrus fruits, especially lemons, limes, and grapefruits.
  • papayas and melons.
  • pumpkins, sweet potatoes, and yams.
  • avocados and olives.
  • tomatoes.
  • carrots, beets, and turnips.
  • cruciferous vegetables, such as broccoli, cauliflower, and Brussels sprouts.

Does Gilbert's syndrome cause itching?

Many people with Gilbert syndrome have no symptoms. Extremely high levels of bilirubin can cause itching, but this does not occur in Gilbert's syndrome, because the levels of bilirubin are not that high.

Can I drink alcohol with high bilirubin?

When the liver is badly damaged by high intake of alcohol, it becomes swollen. This swelling blocks the removal of bilirubin, and bilirubin levels then rise in the blood. A raised bilirubin level indicates serious long term damage to your liver. As the swelling reduces, the bilirubin level can go back to normal.

Why is my bilirubin slightly elevated?


Elevated levels may indicate liver damage or disease. Higher than normal levels of direct bilirubin in your blood may indicate your liver isn't clearing bilirubin properly. One common, and harmless, cause of elevated bilirubin is Gilbert's syndrome, a deficiency in an enzyme that helps break down bilirubin.

How high can bilirubin get?

Typically, bilirubin levels fall somewhere between 0.3 and 1.2 milligrams per deciliter (mg/dL). Anything above 1.2 mg/dL is usually considered high. The condition of having high bilirubin levels is called hyperbilirubinemia.

What is indirect bilirubin blood test?

A bilirubin test measures total bilirubin. It can also give levels of two different types of bilirubin: unconjugated and conjugated. Unconjugated (“indirect”) bilirubin. This is the bilirubin created from red blood cell breakdown. It travels in the blood to the liver.