What is the stimulus for calcitonin secretion?

Asked By: Lesa Nispel | Last Updated: 30th March, 2020
Category: medical health thyroid disorders
4.3/5 (334 Views . 15 Votes)
Calcitonin secretion is stimulated by increases in the serum calcium concentration and calcitonin protects against the development of hypercalcemia. Calcitonin is also stimulated by gastrointestinal hormones such as gastrin.

Click to see full answer


Subsequently, one may also ask, what is calcitonin produced by?

Calcitonin is a hormone that is produced in humans by the parafollicular cells (commonly known as C-cells) of the thyroid gland. Calcitonin is involved in helping to regulate levels of calcium and phosphate in the blood, opposing the action of parathyroid hormone.

One may also ask, what happens when thyroid releases calcitonin? Calcitonin is released by the thyroid gland if the amount of calcium in the bloodstream is high. Calcitonin decreases the amount of calcium and phosphorus in the blood. It does this by slowing the activity of cells found in bone, called osteoclasts. These cells cause calcium to be released as they 'clean' bone.

Also asked, what type of stimuli causes the release of calcitonin and PTH?

Low blood calcium levels cause the production and secretion of PTH. In contrast, elevated blood calcium levels inhibit secretion of PTH and trigger secretion of the thyroid hormone calcitonin.

What is the function of the hormone calcitonin?

Calcitonin is a hormone that the C-cells in the thyroid gland produce and release. It opposes the action of the parathyroid hormone, helping to regulate the blood's calcium and phosphate levels.

35 Related Question Answers Found

What is the opposite of calcitonin?

Parathyroid Hormone. This hormone is produced in the parathyroid gland. It acts opposite calcitonin and causes calcium to be released from the bones.

What kind of cancer does calcitonin cause?

Calcitonin-producing tumor
An experiment of nature is medullary thyroid cancer (MTC), an unusual but not rare tumor of the parafollicular (C) cells of the thyroid.

What are the side effects of calcitonin?

Nausea, abdominal pain, diarrhea, vomiting, or flushing may occur. Using this medication at bedtime may help to decrease these side effects. Swelling/redness at injection site, a salty taste in mouth, increased urination, or loss of appetite may also occur.

What happens if you have too much calcitonin?

If too much calcitonin is found in the blood, it may be a sign of a type of thyroid cancer called medullary thyroid cancer (MTC). High levels may also be a sign of other thyroid diseases that can put you at a higher risk for getting MTC.

Does calcitonin build bone?


Calcitonin is a hormone naturally produced in the thyroid. When given to patients with osteoporosis, calcitonin produces modest increases in bone mass because it slows the rate at which osteoclasts absorb bone. Only women who are at least five years past menopause can take calcitonin.

How long can you take calcitonin?

Calcitonin is used as a short-term treatment (for 2–4 weeks) to help prevent bone loss if you're immobilised following an osteoporotic fracture. It may be given by injection: under the skin (subcutaneous injection) into a muscle (intramuscular injection).

Is calcitonin a steroid?

Calcitonin. Chr. Calcitonin is a 32 amino acid peptide hormone secreted by parafollicular cells (also known as C cells) of the thyroid gland in humans, and in many other animals in the ultimopharyngeal body. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH).

What is considered a high calcitonin level?

Patients with calcitonin levels >100 pg/mL have a high risk for medullary thyroid carcinoma (~90%–100%), whereas patients with values from 10 to 100 pg/mL (normal values: <8.5 pg/mL for men, < 5.0 pg/mL for women; immunochemiluminometric assay) have a <25% risk for medullary thyroid carcinoma.

Which type of stimuli causes the release of TSH?

Humoral Stimuli
A humoral stimulus refers to the control of hormone release in response to changes in extracellular fluids, such as the ion concentration in the blood. For example, a rise in blood glucose levels triggers the pancreatic release of insulin.

How does negative feedback affect the bodies hormones?


In negative feedback systems, a stimulus causes the release of a substance whose effects then inhibit further release. In this way, the concentration of hormones in blood is maintained within a narrow range. A number of endocrine glands release hormones when stimulated by hormones released by other endocrine organs.

What are the three types of stimuli that control hormone secretion?

There are three mechanisms by which endocrine glands are stimulated to synthesize and release hormones: humoral stimuli, hormonal stimuli, and neural stimuli.

What are the two basic mechanisms of hormone action?

There are two major mechanisms, second-messenger mechanisms and direct gene activation, by which the hormone activates the target cell. Direct Gene Activation. Steroid hormones pass through plasma membrane (they're lipid soluble) and attach to receptor molecules that are inside the cell.

What gland produces PTH?

The parathyroid glands lie just behind the thyroid glands in the neck. The parathyroid glands (light pink) produce parathyroid hormone, which increases levels of calcium in the blood. The parathyroid glands are small pea-sized glands located in the neck just behind the butterfly-shaped thyroid gland.

How do you release hormones?

Here are 11 evidence-based ways to increase human growth hormone (HGH) levels naturally.
  1. Lose body fat.
  2. Fast intermittently.
  3. Try an arginine supplement.
  4. Reduce your sugar intake.
  5. Don't eat a lot before bedtime.
  6. Take a GABA supplement.
  7. Exercise at a high intensity.
  8. Take beta-alanine and/or a sports drink around your workouts.

What is the target organ for calcitonin?


In particular, calcitonin has the ability to decrease blood calcium levels at least in part by effects on two well-studied target organs: Bone: Calcitonin suppresses resorption of bone by inhibiting the activity of osteoclasts, a cell type that "digests" bone matrix, releasing calcium and phosphorus into blood.

Is insulin humoral or hormonal?

A humoral stimulus refers to the control of hormone release in response to changes in extracellular fluids such as blood or the ion concentration in the blood. For example, a rise in blood glucose levels triggers the pancreatic release of insulin.

What is behind the thyroid gland?

Parathyroid glands are four small glands of the endocrine system which regulate the calcium in our bodies. Parathyroid glands are located in the neck behind the thyroid where they continuously monitor and regulate blood calcium levels.