How does calcitonin decrease calcium?
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Subsequently, one may also ask, can calcitonin cause hypocalcemia?
When bone turnover is very high, calcitonin-mediated suppression of osteoclast activity can lead to hypocalcemia, and this phenomenon is utilized in the treatment of hypercalcemia with calcitonin. After calcitonin-induced hypocalcemia, compensatory activation of the PTH-vitamin D axis occurs to normalize serum calcium.
Similarly, what causes calcitonin? Calcitonin is a hormone that the C-cells in the thyroid gland produce and release. It opposes the action of the parathyroid hormone, helping to regulate the blood's calcium and phosphate levels. How does calcitonin work? Calcitonin works to control calcium and potassium levels.
Correspondingly, does calcitonin increase or decrease blood calcium levels?
Parathyroid hormone acts to increase blood calcium levels, while calcitonin acts to decrease blood calcium levels. This interaction between parathyroid hormone and calcitonin is also an important part of bone remodeling.
How is calcitonin stimulated?
Calcitonin secretion is stimulated by increases in the serum calcium concentration and calcitonin protects against the development of hypercalcemia. Calcitonin is also stimulated by gastrointestinal hormones such as gastrin.