What is center to center pull?
Thereof, should drawer handles be centered?
Most drawer pulls are centered on the drawer fronts, but if the cabinet you're working on has two or three drawers the same size and one larger one at the bottom, install the bottom knob (or pull) higher than the center of that drawer front. Install it so all the knobs on the cabinet are spaced evenly.
Keeping this in view, what are standard drawer pull sizes?
For standard size cabinetry (dimensions of 12″ – 36″) the most common pull sizes are 3”, 4”, 96mm, and 128mm center to center (from one screw hole to another). Standard knob sizes are 1 1/4″ or 1 3/8″.
Pulls should be placed horizontally on drawers. For small drawers (less than 24'' wide) center the knobs or pulls in both directions. Just like on larger drawers, pulls should be placed horizontally. Knobs and pulls can also be placed centered at the very top of the drawer panel, where the drawer rail begins.