What is anti e Isoimmunization?
Also asked, what is anti E antibody?
Anti-E is an IgG antibody directed against the E antigen in the Rh blood group system. Anti-E is implicated in Hemolytic Transfusion Reactions and Hemolytic Disease of the Fetus and Newborn.
Likewise, what does Isoimmunization mean? Medical Definition of isoimmunization : production by an individual of antibodies against constituents of the tissues of another individual of the same species (as when transfused with blood from one belonging to a different blood group) — called also alloimmunization.
In respect to this, is Anti e clinically significant?
CLINICAL: Anti-E is a fairly common immune antibody that may cause hemolytic transfusion reactions or may be a rare cause of HDN. Transfusion should be made with E-negative blood. TECHNICAL: Anti-E is usually an IgG antibody reactive by antiglobulin or enzyme techniques.
How does anti e affect pregnancy?
1. Introduction. Antibodies with anti-E specificity are detected in 14–20% of pregnant women and it is one of the most common non-D Rhesus (Rh) antibody in the pathogenesis of neonatal hemolytic disease [1, 2]. However, anti-E is rarely associated with severe hemolytic anemia in the fetus [3, 4].