What is angiotensinogen and renin?
Keeping this in consideration, when renin is released from the kidney?
The Release of Renin Renin is an enzyme released by the juxtaglomerular cells of the kidneys in response to low blood pressure, causing the transformation of angiotensinogen to angiotensin I.
Subsequently, question is, how is renin angiotensin system activated? The renin-angiotensin system, as a whole, responds to both short-term and long-term variations in blood pressure. It is activated by sudden drops in blood pressure, such as those that occur after blood loss, but is also stimulated by smaller, less dramatic blood pressure fluctuations.
Just so, what triggers angiotensinogen release?
The liver creates and releases a protein called angiotensinogen. This is then broken up by renin, an enzyme produced in the kidney, to form angiotensin I. As it passes in the bloodstream through the lungs and kidneys, it is further metabolised to produce angiotensin II by the action of angiotensin-converting enzyme.
How does renin affect aldosterone?
Renin cleaves the blood protein angiotensinogen to form angiotensin I, which is then converted by a second enzyme to angiotensin II. Angiotensin II causes blood vessels to constrict, and it stimulates aldosterone production. Overall, this raises blood pressure and keeps sodium and potassium at normal levels.