What causes angiotensinogen to be released?
Consequently, what causes the release of angiotensinogen?
The liver creates and releases a protein called angiotensinogen. This is then broken up by renin, an enzyme produced in the kidney, to form angiotensin I. This increases water reabsorption in the kidney to increase blood volume and blood pressure.
Subsequently, question is, what stimulates the release of aldosterone? Renin acts on a protein circulating in the plasma called angiotensinogen, cleaving this substance into angiotensin I. Angiotensin I is subsequently converted to angiotensin II, which stimulates the release of aldosterone from the adrenal glands.
Also asked, what causes the release of renin?
Renin is secreted from juxtaglomerular kidney cells, which sense changes in renal perfusion pressure, via stretch receptors in the vascular walls. The juxtaglomerular cells are also stimulated to release renin by signaling from the macula densa.
Where is angiotensinogen synthesized?