How significant was Edward Jenner to the development of medicine?

Asked By: Stanford Schmiedle | Last Updated: 26th January, 2020
Category: medical health vaccines
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Edward Jenner (1749-1823) Edward Jenner was an English country doctor who introduced the vaccine for smallpox. Previously a keen practitioner of smallpox inoculation, Jenner took the principle a stage further by inducing immunity against this killer disease via exposure to a harmless related disease, cowpox.

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Likewise, what was the significance of Edward Jenner?

Also known as the “Father of Immunology”, Edward Anthony Jenner was an English scientist and is famous for his discovery of the smallpox vaccine. This was the first successful vaccine ever to be developed and remains the only effective preventive treatment for the fatal smallpox disease.

Additionally, why is Edward Jenner important to the population explosion? Jenner's work is widely regarded as the foundation of immunology—despite the fact that he was neither the first to suggest that infection with cowpox conferred specific immunity to smallpox nor the first to attempt cowpox inoculation for this purpose. Edward Jenner (1749–1823).

Herein, what did Edward Jenner contribute to humanity?

The steps taken by Edward Jenner to create vaccination, the first vaccine for smallpox. Jenner did this by inoculating James Phipps with cowpox, a virus similar to smallpox, to create immunity, unlike variolation, which used smallpox to create an immunity to itself.

How did Edward Jenner's vaccine work?

On May 14, 1796, Jenner took fluid from a cowpox blister and scratched it into the skin of James Phipps, an eight-year-old boy. A single blister rose up on the spot, but James soon recovered. On July 1, Jenner inoculated the boy again, this time with smallpox matter, and no disease developed. The vaccine was a success.

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Where did Edward Jenner make his discovery?

Edward Jenner (1749 - 1823)
In 1772, he returned to Berkeley and spent most the rest of his career as a doctor in his native town. In 1796, he carried out his now famous experiment on eight-year-old James Phipps. Jenner inserted pus taken from a cowpox pustule and inserted it into an incision on the boy's arm.

What was the first vaccine?

Smallpox vaccine, the first successful vaccine to be developed, was introduced by Edward Jenner in 1796. He followed up his observation that milkmaids who had previously caught cowpox did not later catch smallpox by showing that inoculated cowpox protected against inoculated smallpox.

What is Variolation treatment?

Variolation or inoculation was the method first used to immunize an individual against smallpox (Variola) with material taken from a patient or a recently variolated individual, in the hope that a mild, but protective, infection would result.

How many people did smallpox kill?


The scourge of the world
An estimated 300 million people died from smallpox in the 20th century alone. This virulent disease, which kills a third of those it infects, is known to have co-existed with human beings for thousands of years.

How many lives did Edward Jenner save?

5, Englishman Edward Jenner (1749-1823), whose discovery of the smallpox vaccine — the very first vaccine — has saved about 530 million lives. In fact, many of these heroes worked on vaccines that have spared untold numbers of people from premature death.

Why was the vaccine invented?

Louis Pasteur furthered the concept through his work in microbiology. The immunization was called vaccination because it was derived from a virus affecting cows (Latin: vacca 'cow'). Smallpox was a contagious and deadly disease, causing the deaths of 20–60% of infected adults and over 80% of infected children.

Why is smallpox important to history?

Waves of epidemics wiped out large rural populations. The establishment of the disease in Europe was of special importance, for this served as the endemic reservoir from which smallpox spread to other parts of the world, as an accompaniment of successive waves of European exploration and colonization.

How did the smallpox vaccine impact the world?

Further testing proved conclusively that the cowpox virus was able to build immunity against smallpox. Using his theory, similar vaccines were later created for diseases such as yellow fever, mumps, rubella and tetanus.

What is the history of vaccines?


First vaccines
Edward Jenner invented a method to protect against smallpox in 1796. The next routinely recommended vaccines were developed early in the 20th century. These included vaccines that protect against pertussis (1914), diphtheria (1926), and tetanus (1938).

How did smallpox originate?

Early Victims. Smallpox is thought to have originated in India or Egypt at least 3,000 years ago. The earliest evidence for the disease comes from the Egyptian Pharaoh Ramses V, who died in 1157 B.C. His mummified remains show telltale pockmarks on his skin. More than three million Aztec succumbed to the disease.

What is difference between smallpox and cowpox?

Cowpox is similar to, but much milder than, the highly contagious and often deadly smallpox disease. Once vaccinated, a patient develops antibodies that make them immune to cowpox, but they also develop immunity to the smallpox virus, or Variola virus.

When did smallpox end?

Since then, the only known cases were caused by a laboratory accident in 1978 in Birmingham, England, which killed one person and caused a limited outbreak. Smallpox was officially declared eradicated in 1979.

What was the pox in England?

Smallpox is one of two infectious diseases to have been eradicated, the other being rinderpest in 2011. The term "smallpox" was first used in Britain in the early 16th century to distinguish the disease from syphilis, which was then known as the "great pox".

How does a vaccine work?


A vaccine works by training the immune system to recognize and combat pathogens, either viruses or bacteria. By injecting these antigens into the body, the immune system can safely learn to recognize them as hostile invaders, produce antibodies, and remember them for the future.

Who invented vaccinations What purpose does it serve?

Edward Jenner inoculated 8-year-old James Phipps with cowpox as a way to protect him from smallpox. Jenner used the term "vaccination," "vacca" being Latin for "cow." In fact, it has been recognized for centuries that some diseases never reinfect a person after recovery.

How is smallpox spread?

Smallpox spreads from contact with infected persons. Generally, direct and fairly prolonged face-to-face contact is required to spread smallpox from one person to another. Smallpox also can be spread through direct contact with infected bodily fluids or contaminated objects such as bedding or clothing.