Why was Contac 400 discontinued?

A common ingredient of cold and flu remedies has been banned in the US, following a report linking it to an increased risk of haemorrhagic stroke. Brands containing PPA include Contac 400, Benylin Day & Night, Day Nurse and a Vicks cold cure.

People also ask, why was phenylpropanolamine taken off the market?

Phenylpropanolamine. Phenylpropanolamine has both α- and β-adrenergic agonist effects and is used primarily in the treatment of urinary incontinence in dogs. The drug was taken off of the market for use in humans because of the risk of stroke.

Also Know, what is in Contac cold medicine? Active Ingredients: Day Formula: In Each Caplet: Acetaminophen (500 Mg), Phenylephrine Hydrochloride (5 Mg). Night Formula: In Each Caplet: Acetaminophen (500 Mg), Chlorpheniramine Maleate (2 Mg), Phenylephrine Hydrochloride (5 Mg). Day Formula: Purpose: Pain Reliever/Fever Reducer, Nasal Decongestant.

Also question is, is comtrex still on the market?

And the drug makers SmithKline Beecham and Bristol-Myers Squibb said today that they would no longer market cold remedies containing the chemical. A spokesman for Bristol-Myers Squibb, which sells the cold remedies Comtrex and Naldecon, said the company was moving to reformulate its products.

How many cold relief tablets can I take?

For the symptomatic relief of colds, influenza and sinus congestion. Adults and Children over 12 years: 2 tablets with water followed by 1 or 2 tablets every four hours, if needed, up to a maximum of 8 tablets in 24 hours. Not to be taken more frequently than every four hours. Children under 12 years: Not recommended.

39 Related Question Answers Found

Is Contac 400 still available?

Dangerous remedies. A common ingredient of cold and flu remedies has been banned in the US, following a report linking it to an increased risk of haemorrhagic stroke. Brands containing PPA include Contac 400, Benylin Day & Night, Day Nurse and a Vicks cold cure.

Why actifed is banned?

In the U.S., the formula was changed in 2006 due to a change in the legal environment; at the same time, distribution of the product was limited to certain stores. The United States Food and Drug Administration, FDA, lists Actifed as discontinued.

Can you still buy Contac cold medicine?

Contac^® Cold + Flu can be purchased at retail locations nationwide.

Is phenylpropanolamine safe?

In 1976, one expert panel recommended that phenylpropanolamine be generally recognized as safe and effective as a nasal decongestant, and in 1982 another expert panel recommended that phenylpropanolamine be generally recognized as safe and effective for weight control.

What class of drug is phenylpropanolamine?

Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant.

Why was pseudoephedrine taken off the market?

Pseudoephedrine was withdrawn from sale in 1989 due to concerns about adverse cardiac side effects.

Why was Sudafed taken off the market?

All products from the makers of SUDAFED^® contain a nasal decongestant, either pseudoephedrine or phenylephrine. Because, pseudoephedrine can be used to illegally manufacture methamphetamines (also known as meth), federal regulations require that it be sold behind the pharmacy or service counter.

Is phenylpropanolamine the same as phenylephrine?

Phenylephrine and phenylpropanolamine are decongestants. They constrict (shrink) blood vessels (veins and arteries). Brompheniramine/phenylephrine/phenylpropanolamine is used to treat nasal congestion and sinusitis (inflammation of the sinuses) associated with allergies, hay fever, and the common cold.

How often can you take Comtrex?

adults and children 12 years and over: take 2 caplets every 4 hours. swallow whole - do not crush, chew, or dissolve. do not take more than 10 caplets in 24 hours.

Do they still make dimetapp?

Dimetapp is a brand of over-the-counter cold and allergy medicines manufactured by Pfizer (formerly Wyeth). The same product with a "Citrus Burst" flavour additive was also manufactured and distributed by Wyeth but branded and marketed as "Alavert" (not "children's").

What allergy medicine was taken off the market?

The FDA said it intends to withdraw its approval of Seldane and Seldane D antihistamine and generic versions, all of which contain terfenadine. Millions of people have used Seldane, which was the first drug to relieve allergy symptoms without inducing drowsiness.

What is the active ingredient in dristan?

Dristan Cold Multi-Symptom Tablets contain three active ingredients: acetaminophen, USP 325 mg (a pain reliever and fever reducer), chlorpheniramine maleate, USP 2 mg (an antihistamine), and phenylephrine HCl, USP 5 mg (a nasal decongestant).

Does comtrex make you sleepy?

Drowsiness, dizziness, blurred vision, upset stomach, nausea, nervousness, constipation, or dry mouth/nose/throat may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What is Comtrex cold?

Acetaminophen is a pain reliever and fever reducer. Dextromethorphan is a cough suppressant. Comtrex Cold & Cough is a combination medicine used to treat headache, fever, body aches, cough, stuffy nose, and sinus congestion caused by allergies, the common cold, or the flu.

What is ornade?

Chlorpheniramine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in the body. Chlorpheniramine prevents sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever. This reduces the blood flow to certain areas and allows nasal passages to open up.

Is triaminic discontinued?

After careful consideration, GlaxoSmithKline (GSK) has decided to discontinue the manufacturing and distribution of Children's Triaminic^® Thin Strips^® as of January 1, 2012.

Why is proin a controlled substance?

Proin is a supplemental adrenergic agent, which means it mimics adrenaline or epinephrine, which are the hormones needed to trigger vasoconstriction, the constriction of blood vessels. Proin is a classified controlled substance in Arkansas, Iowa, Illinois, Louisiana and Oregon.