Which drug is used by nasal route?

Asked By: Arianna Kromker | Last Updated: 13th January, 2020
Category: medical health pharmaceutical drugs
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Steroids, antiasthma medications such as salbutamol, ipratropium, montelukast and a large number of inhalational anaesthetic agents are being used commonly. The recent developments in intranasal drug delivery systems are prodigious.

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Thereof, what drugs can be given intranasally?

There are many classes of medications that may be used intranasally, many of which are applicable to the pre-hospital and emergency setting. These medications include antiepileptics, opiate analgesics and opiate antagonists, sedatives, topical anesthetics, glucagon for hypoglycemia, and agents for epistaxis control.

Furthermore, what is intranasal use? Intranasal drug administration has a long tradition and was and is still used for medical as well as recreational purposes. The most common use is for treatment of local symptoms e.g. nasal congestion in the course of a common rhinitis or inflammation linked to allergic rhinitis.

In this manner, how are drugs absorbed through the nose?

Absorption of drug via the nasal cavity can be described as diffusion of drug into system circulation via the nasal mucosa. Mucosal absorption via the nasal cavity usually follows: drug release, penetration (entry into a layer), permeation (transition of a layer), and absorption (uptake into the vascular system).

What are the four routes of drug administration?

Each route has specific purposes, advantages, and disadvantages.

  • Oral route. Many drugs can be administered orally as liquids, capsules, tablets, or chewable tablets.
  • Injection routes.
  • Sublingual and buccal routes.
  • Rectal route.
  • Vaginal route.
  • Ocular route.
  • Otic route.
  • Nasal route.

34 Related Question Answers Found

What is a nasal atomizer?

The MAD Nasal Intranasal Mucosal Atomization Device from Teleflex is the safe and painless way to deliver medications*. Atomizes in any position. The soft, conical plug on the tip forms a seal with the nostril, preventing expulsion of fluid. The spray atomizes drugs into a fine mist of particles 30-100 microns in size.

How do I give Midazolam Intranasal?

Lie the child on a flat surface. Place the assembled atomizer and the syringe firmly on the nostril. Press the plunger of the syringe quickly to administer about half of the volume as atomised spray into a nostril. Move the device over to the opposite nostril and administer the remaining medication into that nostril.

Can lorazepam be given intranasally?

It can be given intravenously (IV), intramuscularly (IM), buccally or intranasally (IN). Intravenous lorazepam (100 μg/kg) is recommended as first line treatment of acute childhood seizures in resource-rich settings when IV access is available.

How do you use a nasal atomizer?

Place the tip of the atomizer snugly inside the nostril. Aim slightly up and out toward the top of the ear. 11. Quickly compress the syringe plunger to give half of the medicine into the nostril.

Is intranasal midazolam FDA approved?


Midazolam nasal spray is the first and only FDA-approved nasal option for treating seizure clusters. It is packaged as a single-use treatment that can be carried with a patient and administered by persons who are not healthcare professionals.

What does intranasally mean?

Definition of intranasal. : lying within or administered by way of the nasal structures.

How long does intranasal midazolam last?

RESULTS: There was rapid onset of sedation with the maximal effect between 8 and 15 minutes. This sedation lasted for 25-40 minutes in Groups A and B and for 60 minutes in Group C.

How is intranasal lidocaine administered?

Nasal intubations
  1. Load a 5cc syringe with 4.5 ml of 4% lidocaine and attach nasal atomizer (adult dose)
  2. Give the patient a tissue to capture any runoff solution.
  3. Place atomizer within the selected nostril.
  4. Briskly compress syringe to administer 1.5 ml of atomized spray into the nose.

Does Nasal Spray enter the bloodstream?


Nasal sprays are used to deliver medications into your nostrils. The lining of your nose is rich in blood vessels, which means it can easily absorb medications into your bloodstream.

When should I use nasal spray?

Nasal sprays are often used to treat symptoms of allergies and colds such as congestion, sneezing, and runny nose. But they can be used for other purposes as well. For instance, Tamiflu nasal spray, which contains the drug oseltamivir, can be used to treat the flu.

What are parenteral drugs?

Parenteral drugs refer to drugs using non-oral means of administration by injecting the drug directly into the body typically through three common routes of administration: intramuscular, subcutaneous and intravenous.

How do you properly snort?

Snorting is a means of using both recreational and prescription drugs. The drug is typically ground up into a powder by chopping it finely with a razor blade on a hard surface. It may then be divided into "lines," and a straw or rolled paper may be used to inhale the drug up into the nasal passages.

Is intranasal a parenteral route?

Intravenous, intramuscular, topical, otic, conjunctival, nasal, inhalation, and subcutaneous are parenteral routes of administration. The intravenous route of medication is given directly into a vein.

How do you heal a sore in your nose?


Home treatments
  1. applying petroleum jelly or using nasal saline spray to keep the nasal passages from drying out.
  2. using creams like pain-free Neosporin to fight infection and reduce pain.
  3. leaving scabs alone and not picking at them.
  4. not smoking or using drugs.

What is the abbreviation for intranasal?

Intranasal. Mistaken as "IM" or "IV" Use "intranasal" or "NAS"

Who invented nasal spray?

It was developed from xylometazoline at E. Merck Darmstadt by Fruhstorfer in 1961. Oxymetazoline is generally available as a nasal spray.