What is the pathophysiology of gastroesophageal reflux disease Gord?
Accordingly, what is the pathophysiology of gastroesophageal reflux disease?
The pathogenesis of gastroesophageal reflux disease (GERD) is complex and involves changes in reflux exposure, epithelial resistance, and visceral sensitivity. The gastric refluxate is a noxious material that injures the esophagus and elicits symptoms.
One may also ask, what is the injury in gastroesophageal reflux? Gastroesophageal reflux disease occurs when the amount of gastric juice that refluxes into the esophagus exceeds the normal limit, causing symptoms with or without associated esophageal mucosal injury (ie, esophagitis; see the image below). Peptic esophagitis.
Similarly one may ask, what is pathological acid reflux?
GERD Pathology. Gastroesophageal reflux disease, known as GERD or heartburn, can occur at any age. There is a genetic component to GERD. Heartburn begins when hydrochloric acid and/or a food bolus are regurgitated up from the stomach, and passes up through a circular muscle called the lower esophageal sphincter (LES).
What is the difference between Gord and GERD?
According to the ACG, GERD is acid reflux that occurs more than a couple of times per week. But the symptoms are the same as those of acid reflux, such as the burning feeling in your chest and the sensation that your stomach contents are in your throat.