What is the most harmful mutation?
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Also to know is, what are some harmful mutations?
Harmful mutations may cause genetic disorders or cancer. A genetic disorder is a disease caused by a mutation in one or a few genes. A human example is cystic fibrosis. A mutation in a single gene causes the body to produce thick, sticky mucus that clogs the lungs and blocks ducts in digestive organs.
Similarly, what are the 4 types of mutation? There are three types of DNA Mutations: base substitutions, deletions and insertions.
- Base Substitutions. Single base substitutions are called point mutations, recall the point mutation Glu -----> Val which causes sickle-cell disease.
Beside this, what kind of mutation is the most dangerous?
Which is worse missense or nonsense mutation?
So it's conceivable that a frame shift could allow for a partially functional protein to be made, whereas a nonsense mutation at the same spot might result in no protein at all. A missense only affects a single amino acid, so clearly it would be less detrimental to the final protein than the other two.