What is the antidote for malignant hyperthermia?
Also question is, how do you treat malignant hyperthermia?
As soon as malignant hyperthermia is suspected, doctors must act rapidly to treat the condition and prevent complications. The first and most important step is to immediately stop giving the triggering medication and to stop the surgery. Doctors then give the drug dantrolene (Dantrium). Dantrolene relaxes the muscles.
Also Know, how is malignant hyperthermia detected? The caffeine halothane contracture test (CHCT) is the criterion standard for establishing the diagnosis of malignant hyperthermia (MH). The test is performed on freshly biopsied muscle tissue at 30 centers worldwide; one of these centers is located in Canada, and four are located in the United States.
Furthermore, what is dantrolene the antidote for?
Dantrolene produces relaxation of skeletal muscle without causing complete paralysis, and is the only xenobiotic proven to be effective for both treatment and prophylaxis of malignant hyperthermia (MH).
What is the first sign of malignant hyperthermia?
Early clinical signs of MH include an increase in end-tidal carbon dioxide (even with increasing minute ventilation), tachycardia, muscle rigidity, tachypnea, and hyperkalemia. Later signs include fever, myoglobinuria, and multiple organ failure. Anesthetics are inconsistent in triggering MH.