What is ceftriaxone target?

Asked By: Geraxane Gambero | Last Updated: 30th March, 2020
Category: medical health infectious diseases
4.9/5 (126 Views . 13 Votes)
Like other third-generation cephalosporins, ceftriaxone is active against Citrobacter spp., Serratia marcescens, and beta-lactamase-producing strains of Haemophilus and Neisseria. However, unlike ceftazidime and cefoperazone, ceftriaxone does not have useful activity against Pseudomonas aeruginosa.

Click to see full answer


Similarly, what bacteria does ceftriaxone treat?

Ceftriaxone injection is used to treat certain infections caused by bacteria such as gonorrhea (a sexually transmitted disease), pelvic inflammatory disease (infection of the female reproductive organs that may cause infertility), meningitis (infection of the membranes that surround the brain and spinal cord), and

Secondly, is ceftriaxone broad spectrum antibiotic? Ceftriaxone: a beta-lactamase-stable, broad-spectrum cephalosporin with an extended half-life. Beam TR Jr. Ceftriaxone has been used to treat serious bacterial infections in neonates, infants, children and adults.

Considering this, what is ceftriaxone used for?

Ceftriaxone (ceftriaxone sodium and dextrose) Injection is an antibacterial drug used to treat conditions such as lower respiratory tract infections, skin and skin structure infections, urinary tract infections, pelvic inflammatory disease, bacterial septicemia, bone and joint infections, and meningitis.

How quickly does ceftriaxone work?

Ceftriaxone was completely absorbed following IM administration with mean maximum plasma concentrations occurring between 2 and 3 hours post-dose. Multiple IV or IM doses ranging from 0.5 to 2 gm at 12- to 24-hour intervals resulted in 15% to 36% accumulation of ceftriaxone above single dose values.

36 Related Question Answers Found

How long does ceftriaxone last in the body?

Elimination: The average elimination half-life in healthy adults is 5.8–8.7 hours. In people with renal impairment, the average elimination half-life increases to 11.4–15.7 hours.

Is ceftriaxone a strong antibiotic?

Ceftriaxone is a cephalosporin (SEF a low spor in) antibiotic. It works by fighting bacteria in your body. Ceftriaxone is used to treat many kinds of bacterial infections, including severe or life-threatening forms such as meningitis.

What antibiotic is good for STD?

If you have this STD, your doctor will likely prescribe two antibiotics: ceftriaxone and either azithromycin (Zithromax, Zmax) or doxycycline (Monodox, Vibramycin). Ceftriaxone is given as a one-time injection -- usually a dose of 250 milligrams (mg).

How is ceftriaxone given?

1g ceftriaxone should be dissolved in 3.5ml of 1% Lidocaine Injection BP. The solution should be administered by deep intramuscular injection. Ceftriaxone can be administered by intravenous infusion over at least 30 minutes (preferred route) or by slow intravenous injection over 5 minutes.

What class of drug is Ceftriaxone?


cephalosporin antibiotics

Does alcohol interfere with ceftriaxone?

Partners of people who are treated should not have any sexual contact with the treated partner for seven days after his or her treatment. It is best not to drink alcohol for up to 48 hours after the injection. This medication is not known to be harmful during pregnancy or breastfeeding.

What is the side effect of ceftriaxone?

SIDE EFFECTS: Swelling, redness, pain, or soreness at the injection site may occur. This medication may also infrequently cause loss of appetite, nausea, vomiting, diarrhea, or headache. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Where do you inject ceftriaxone?

Ceftriaxone is injected into a muscle, or into a vein through an IV. A healthcare provider will give you this injection when ceftriaxone is used to prevent infection from surgery.

Can ceftriaxone make you tired?

Rocephin Side Effects
If any of these symptoms continue or get worse, let your doctor know right away. Other symptoms could include bruising or bleeding more easily, chest pain, trouble breathing, mood changes like confusion, or unusual tiredness or weakness.

Is there ceftriaxone tablet?


Ceftriaxone is used to treat a wide variety of bacterial infections. Ceftriaxone belongs to a class of drugs known as cephalosporin antibiotics. It works by stopping the growth of bacteria. Ceftriaxone is available under the following different brand names: Rocephin.

Can ceftriaxone cure candidiasis?

Four single-dose therapies are now recommended for the management of uncomplicated gonococcal infections, including 400 mg of cefixime, 500 mg of ciprofloxacin, 125 mg of ceftriaxone or 400 mg of ofloxacin. Single-dose therapy with 150 mg of oral fluconazole is a recommended treatment for vulvovaginal candidiasis.

What kind of antibiotic is ceftriaxone?

Rocephin (ceftriaxone) is a cephalosporin antibiotic. It works by fighting bacteria in your body. Rocephin is used to treat many kinds of bacterial infections, including severe or life-threatening forms such as meningitis. Rocephin is also used to prevent infection in people having certain types of surgery.

Is ceftriaxone same as penicillin?

Cephalothin, cephalexin, cefadroxil, and cefazolin confer an increased risk of allergic reaction among patients with penicillin allergy. Cefprozil, cefuroxime, cefpodoxime, ceftazidime, and ceftriaxone do not increase risk of an allergic reaction.

How do you reconstitute ceftriaxone?

Dilute single dose vials of ceftriaxone with 0.9 ml 1% lidocaine solution (or sterile water) using a 1 ml syringe. Total volume will be approximately 1 ml. 2. Discard syringe and needle used for drawing up lidocaine/sterile water.

Does ceftriaxone treat chlamydia?


Role of ceftriaxone in sexually transmitted diseases. Chlamydial infections are not altered by ceftriaxone, and additional treatment is necessary if Chlamydia is present concurrently with Neisseria gonorrhoeae.

What is ceftriaxone made of?

Rocephin is a sterile, semisynthetic, broad-spectrum cephalosporin antibiotic for intravenous or intramuscular administration. Ceftriaxone sodium is (6R,7R)-7-[2-(2Amino-4-thiazolyl)glyoxylamido]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-astriazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.

What is the strongest antibiotic for bacterial infection?

AMOXICILLIN is a penicillin antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.