What is an advantage of sublingual drug administration compared with other routes of administration?

Asked By: Joycelyn Scharpey | Last Updated: 22nd January, 2020
Category: medical health pharmaceutical drugs
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Sublingual (under the tongue) or buccal (between gum and cheek) administration is advantageous for drugs that have low oral availability because venous drainage from the mouth bypasses the liver. Drugs must be lipophilic and are absorbed rapidly.

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Moreover, what are the advantages of oral route of administration?

The oral administration route is preferred over the various other administration routes of drug delivery due to the many advantages it exhibits. These advantages include safety, good patient compliance, ease of ingestion, pain avoidance, and versatility to accommodate various types of drugs (Sastry et al., 2000).

Secondly, what is the major advantage of intravenous drug administration? The administration of IV medication offers advantages over other routes of administration. Some of the main advantages include: direct access to the circulatory system, a route for administration of drugs and fluids for patients unable to tolerate oral medications and instant drug action and termination.

Similarly, it is asked, what is the advantage of sublingual medication?

Advantages. Sublingual or buccal forms of drugs have their advantages. Because the medication absorbs quickly, these types of administration can be important during emergencies when you need the drug to work right away, such as during a heart attack.

Why is sublingual more effective?

Compared to commonly used tablets, capsules and other oral dosage forms, sublingual absorption is generally much faster and more efficient. Sublingual absorption is efficient. The percent of each dose absorbed is generally higher than that achieved by means of oral ingestion.

38 Related Question Answers Found

What are the 8 routes of drug administration?

Each route has specific purposes, advantages, and disadvantages.
  • Oral route. Many drugs can be administered orally as liquids, capsules, tablets, or chewable tablets.
  • Injection routes.
  • Sublingual and buccal routes.
  • Rectal route.
  • Vaginal route.
  • Ocular route.
  • Otic route.
  • Nasal route.

Why is oral administration of medication the most suitable route?

Oral (PO) administration is the most frequently used route of administration because of its simplicity and convenience, which improve patient compliance. Administration via this route is less desirable for drugs that are irritating to the GI tract or when the patient is vomiting or unable to swallow.

Why is intravenous route used?

The intravenous route is the fastest way to deliver medications and fluid replacement throughout the body, because they are introduced directly into the circulation. Intravenous therapy may be used for fluid volume replacement, to correct electrolyte imbalances, to deliver medications, and for blood transfusions.

Does sublingual bypass the liver?

Medications that are administered sublingually dissolve under the tongue, without chewing or swallowing. Absorption is very quick, and higher drug levels are achieved in the bloodstream by sublingual routes than by oral routes because (1) the sublingual route avoids first-pass metabolism by the liver (Fig.

What are the advantages of inhalation route?

The inhaled route has a number of attractive features for treatment of pulmonary hypertension, including delivery of drug directly to the target organ, thus enhancing pulmonary specificity and reducing systemic adverse effects.

What is the meaning of oral administration?

Oral administration is a route of administration where a substance is taken through the mouth. Many medications are taken orally because they are intended to have a systemic effect, reaching different parts of the body via the bloodstream, for example.

What does method of administration mean?

A route of administration is the means by which a drug or agent enters the body, such as by mouth or by injection. Various routes of administration are possible, including oral, topical, and parenteral. A parenteral route of administration may be required when the oral route cannot be used.

Why do you put vitamin b12 under your tongue?

Sublingual vitamins, which are meant to be taken by dissolving the tab under your tongue, are growing in popularity. They work because the nutrient is absorbed under the tongue and enters the bloodstream directly without having to go through the gastrointestinal tract.

Does medicine absorb faster under tongue?

Sublingual Medicine Administration
The area underneath the tongue has tiny blood capillaries. Therefore, drugs are absorbed directly and very fast into the system without passing through the digestive system.

What is sublingual used for?

Nitroglycerin sublingual tablets are used to treat episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). It is also used just before activities that may cause episodes of angina in order to prevent the angina from occurring.

What drug do you put under your tongue?

What is buprenorphine sublingual? Buprenorphine is an opioid medication. Buprenorphine oral/sublingual (given under the tongue) is used to treat opioid addiction. Other forms of buprenorphine are used to treat moderate to severe pain.

Why put CBD oil under your tongue?

When it comes to CBD which is a natural food supplement, it is in our best interests to get the maximum absorption and as quickly as possible. This is why we suggest you hold the oil under the tongue 60 seconds before swallowing. Truth be known, the longer you can hold it there the better the absorption will be.

Can any medication be taken sublingually?

A pill designed to be given orally will rarely be able to be administered sublingually. An example of a pain medication intended to be taken orally that can be taken sublingually, if you don't mind a slight bitter taste, is hydrocodone. Approximately 1/3 of an oral dose has the same effects when taken sublingually.

What are parenteral drugs?

Parenteral drugs refer to drugs using non-oral means of administration by injecting the drug directly into the body typically through three common routes of administration: intramuscular, subcutaneous and intravenous.

Are sublingual vitamins better?

Sublingual supplements are better for: People who have difficulty swallowing capsules or tablets (including children and the elderly) Rapid absorption and quick distribution of nutrients. Delivery of certain nutrients, such as vitamin B12.

How do you take sublingual b12?

It is best if this medicine (cyanocobalamin sublingual tablets) is taken with a meal. Place under tongue and let dissolve all the way. Do not chew, suck or swallow tablet.

What are the advantages and disadvantages of intravenous?

They cannot eliminate pain. They have the side effects of possibly causing nausea, vomiting, itchiness and/or constipation. They cross the placenta and enter the baby's circulation. They are limited by their universal side effect of sedation for both the mother and her unborn child.