What drugs interact with antidepressants?

Asked By: Geanina Kiessling | Last Updated: 1st January, 2020
Category: healthy living smoking cessation
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Introduction
SSRI Interacting Drug
All Monoamaine oxidase inhibitors (MAOIs), including moclobemide
Fluoxetine & paroxetine (possibly citalopram) Clozapine, haloperidol and risperidone
All Tramadol
All Tricyclic antidepressants

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Considering this, what drugs do SSRIs interact with?

Some of the medications that can interact with some SSRIs include:

  • non-steroidal anti-inflammatory drugs (NSAIDs) – a common type of painkiller that includes ibuprofen, diclofenac or naproxen.
  • antiplatelets – a type of medication used to prevent blood clots, such as low-dose aspirin and clopidogrel.

Also Know, can you take decongestants with antidepressants? Getting back to your question, decongestant medications probably will not interact significantly with your antidepressants. In addition, your doctor can recommend the best decongestant medication that will have the fewest side effects and the fewest interactions with your other medications.

Then, what drugs should not be taken with antidepressants?

When your doctor prescribes you anti-depression pills, they should give you a rundown on the drugs that don't mix with antidepressants.

SSRIs

  • Citalopram (Celexa)
  • Sertraline (Zoloft)
  • Fluoxetine (Prozac)
  • Escitalopram (Lexapro)
  • Fluvoxamine (Luvox)
  • Paroxetine (Paxil)

What medications can you not take with Prozac?

Taking MAO inhibitors with his medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication.

39 Related Question Answers Found

Do SSRIs permanently change your brain?

Depression drugs -- SSRIs -- may reorganize brain plasticity, new research suggests. Summary: Selective serotonin reuptake inhibitors (SSRI) such as Prozac are regularly used to treat severe anxiety and depression. New research investigates physiological changes within the brain that may be caused by SSRI treatment.

Can caffeine cause serotonin syndrome?

Consumption of large amounts of caffeine in tandem with the ingestion of serotonergic medications, particularly antidepressants, may contribute to the development of serotonin syndrome in susceptible patients (Shioda 2004).

Which SSRI has least drug interactions?

Citalopram and sertraline, which have relatively little effect on the P450 system and wash out of the body relatively quickly, are the least likely of the SSRIs to interact with a replacement drug.

What can you not mix with SSRI?

In particular, SSRIs should not be mixed with certain other medications, especially the herbal remedy St. John's wort, monoamine oxidase inhibitors such as phenelzine (Nardil), and clomipramine (Anafranil).

Do antidepressants damage your brain?

Research on animals has found that antidepressants can shrink the connections between brain cells and that these don't grow back after the drugs are stopped. 'I have never seen any convincing evidence showing a psychiatric disease is causing brain damage, but have seen plenty that medication causes brain damage. '

How do SSRIs make you feel?

Antidepressants help relieve the symptoms of depression and associated anxiety. They do not make you euphoric, but simply help you react more realistically in your emotional responses. You may notice, for example, that you take in your stride little things that used to worry you or get you down.

Can you take painkillers with antidepressants?

Antidepressants and painkillers - a dangerous combination. Taking antidepressants together with painkillers can substantially increase the risk of bleeding from the stomach, according to new research by the University of East Anglia.

Which SSRI is best for anxiety?

The antidepressants most widely prescribed for anxiety are SSRIs such as Prozac, Zoloft, Paxil, Lexapro, and Celexa.

What is the most dangerous antidepressant?

TCAs. When compared to other types of antidepressants, tricyclic antidepressants (TCAs) result in the highest number of fatal overdoses. The typical daily dose of the TCA amitriptyline is between 40 and 100 milligrams (mg).

Which antidepressant gives the most energy?

Prozac/Fluoxetine
It gives people more energy than other antidepressants which may not work well for someone with insomnia as well as depression.

How do you know if your antidepressant is working?

Coping With Depression: A Guide to Good Treatment
  1. You skipped a dose — or several.
  2. You experience no relief from depression symptoms after a few months.
  3. You feel a sudden surge of energy — along with the blues.
  4. You're experiencing unpleasant side effects.
  5. Your antidepressant doesn't pack the punch it used to.

Can you stay on antidepressants for life?

Experts recommend people stay on antidepressants for four to nine months after remission, but some keep taking them for years.

What is the best combination of antidepressants?

Bupropion, citalopram, escitalopram, and sertraline were better tolerated than the other antidepressants. Escitalopram and sertraline were found to have the best combination of efficacy and acceptability. Efficacy results.

How long should you stay on antidepressants?

Although it may be tempting to stop medication as your mood lifts, continue taking it for as long as your doctor recommends. Most doctors advise patients to take antidepressants for six months to a year after they no longer feel depressed.

What happens if someone without depression takes antidepressants?

(If a person who isn't depressed takes antidepressants, they do not improve that person's mood or functioning - it's not a "happy pill.") Rarely, people experience apathy or loss of emotions while on certain antidepressants. When this happens, lowering the dose or switching to a different antidepressant may help.

What is the best natural antidepressant?

5 Best Natural Antidepressants
  1. Ginkgo biloba. If you're looking to take the natural approach to treating mild depression, you may want to give ginkgo biloba supplements a try.
  2. 5-hydroxytryptophan (5-HTP)
  3. B vitamins.
  4. S-adenosyl-L-methionine (SAMe)
  5. Zinc.

Why do antidepressants make you suicidal?

However, some evidence suggests that Selective Serotonin Reuptake Inhibitors [SSRIs] may cause worsening of suicidal ideas in vulnerable patients. However, in children and adolescents, there appears to be a bit of increased risk of suicidal ideations and attempts, but not of completed suicides.