What are some non SSRI antidepressants?

Asked By: Christal Dunford | Last Updated: 7th June, 2020
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Switch to a different kind of antidepressant that is not an SSRI, such as bupropion (Wellbutrin®), desvenlafaxine (Pristiq®), duloxetine (Cymbalta®), or venlafaxine (Effexor®). Add an antipsychotic medicine to your SSRI, such as aripiprazole (Abilify®), olanzapine (Zyprexa®), or quetiapine XR (Seroquel XR®).

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Similarly one may ask, are all antidepressants SSRIs?

There are three types: Selective serotonin reuptake inhibitors (SSRIs) are some of the most commonly prescribed antidepressants available. It's a combination of the SSRI antidepressant fluoxetine (Prozac) and another drug approved for bipolar disorder and schizophrenia called olanzapine (Zyprexa).

Additionally, what are some mild antidepressants? Antidepressants that are less effective and less acceptable than sertraline or escitalopram have been prescribed with greater frequency.

  • fluoxetine (Prozac)
  • duloxetine (Cymbalta)
  • escitalopram (Lexapro)
  • paroxetine (Paxil)
  • venlafaxine (Effexor)
  • sertraline (Zoloft).

Additionally, what are common antidepressants?

List of the types of antidepressants

  • citalopram (Celexa)
  • escitalopram (Lexapro)
  • fluoxetine (Prozac, Sarafem, Selfemra, Prozac Weekly)
  • fluvoxamine (Luvox)
  • paroxetine (Paxil, Paxil CR, Pexeva)
  • sertraline (Zoloft)
  • vortioxetine (Trintellix, formerly known as Brintellix)
  • vilazodone (Viibryd)

What is an aminoketone antidepressant?

Bupropion is an atypical antidepressant. It acts as a norepinephrine–dopamine reuptake inhibitor (NDRI) and a nicotinic receptor antagonist. Chemically, bupropion is an aminoketone that belongs to the class of substituted cathinones and is similar to phenethylamines.

38 Related Question Answers Found

Do SSRIs permanently change your brain?

Depression drugs -- SSRIs -- may reorganize brain plasticity, new research suggests. Summary: Selective serotonin reuptake inhibitors (SSRI) such as Prozac are regularly used to treat severe anxiety and depression. New research investigates physiological changes within the brain that may be caused by SSRI treatment.

What is the most dangerous antidepressant?

TCAs. When compared to other types of antidepressants, tricyclic antidepressants (TCAs) result in the highest number of fatal overdoses. The typical daily dose of the TCA amitriptyline is between 40 and 100 milligrams (mg).

Do antidepressants damage your brain?

Research on animals has found that antidepressants can shrink the connections between brain cells and that these don't grow back after the drugs are stopped. 'I have never seen any convincing evidence showing a psychiatric disease is causing brain damage, but have seen plenty that medication causes brain damage. '

Do SSRIs cause weight gain?

Experts say that for up to 25% of people, most antidepressant medications -- including the popular SSRI (selective serotonin reuptake inhibitor) drugs like Lexapro, Paxil, Prozac, and Zoloft -- can cause a weight gain of 10 pounds or more.

Which antidepressant gives the most energy?


Prozac/Fluoxetine
It gives people more energy than other antidepressants which may not work well for someone with insomnia as well as depression.

Do SSRIs change your personality?

Antidepressants Change Personality, Study Suggests. In fact, such drugs may alter two key personality traits linked to depression—neuroticism and extraversion—independently of their effect on depression symptoms.

Are SSRIs dangerous?

Safety issues. SSRIs are generally safe for most people. However, in some circumstances they can cause problems. For example, high doses of citalopram may cause dangerous abnormal heart rhythms, so doses over 40 milligrams (mg) a day should be avoided according to the FDA and the manufacturer.

What antidepressants are not SSRIs?

Switch to a different kind of antidepressant that is not an SSRI, such as bupropion (Wellbutrin®), desvenlafaxine (Pristiq®), duloxetine (Cymbalta®), or venlafaxine (Effexor®). Add an antipsychotic medicine to your SSRI, such as aripiprazole (Abilify®), olanzapine (Zyprexa®), or quetiapine XR (Seroquel XR®).

Can you stay on antidepressants for life?

Experts recommend people stay on antidepressants for four to nine months after remission, but some keep taking them for years.

Do Antidepressants Make You Happy?


Antidepressants help relieve the symptoms of depression and associated anxiety. They do not make you euphoric, but simply help you react more realistically in your emotional responses. You may notice, for example, that you take in your stride little things that used to worry you or get you down.

How do you know if your antidepressant is working?

Coping With Depression: A Guide to Good Treatment
  1. You skipped a dose — or several.
  2. You experience no relief from depression symptoms after a few months.
  3. You feel a sudden surge of energy — along with the blues.
  4. You're experiencing unpleasant side effects.
  5. Your antidepressant doesn't pack the punch it used to.

What happens if you take antidepressants without depression?

(If a person who isn't depressed takes antidepressants, they do not improve that person's mood or functioning - it's not a "happy pill.") Rarely, people experience apathy or loss of emotions while on certain antidepressants. When this happens, lowering the dose or switching to a different antidepressant may help.

What is the best natural antidepressant?

5 Best Natural Antidepressants
  1. Ginkgo biloba. If you're looking to take the natural approach to treating mild depression, you may want to give ginkgo biloba supplements a try.
  2. 5-hydroxytryptophan (5-HTP)
  3. B vitamins.
  4. S-adenosyl-L-methionine (SAMe)
  5. Zinc.

Which antidepressant is best for anxiety?

The antidepressants most widely prescribed for anxiety are SSRIs such as Prozac, Zoloft, Paxil, Lexapro, and Celexa. SSRIs have been used to treat generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, and post-traumatic stress disorder.

Does genetic testing for antidepressants work?


Genetic Tests for Depression Treatment Aren't Effective, Experts Say. Their products — pharmacogenomic tests — aim to predict how someone with depression will respond to medications based on that person's genetic makeup, sparing them from the trial-and-error that often comes with selecting an antidepressant.

Which antidepressant has least side effects?

These medications generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants are. SSRIs include fluoxetine (Prozac), paroxetine (Paxil, Pexeva), sertraline (Zoloft), citalopram (Celexa) and escitalopram (Lexapro).

Why do antidepressants make you suicidal?

However, some evidence suggests that Selective Serotonin Reuptake Inhibitors [SSRIs] may cause worsening of suicidal ideas in vulnerable patients. However, in children and adolescents, there appears to be a bit of increased risk of suicidal ideations and attempts, but not of completed suicides.