How many Holliday junctions are produced in the double stranded break model?
Besides, what is a double Holliday junction?
Holliday junction, cross-shaped structure that forms during the process of genetic recombination, when two double-stranded DNA molecules become separated into four strands in order to exchange segments of genetic information.
Beside above, what is a double strand break? Double-strand DNA breaks. Definition. A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation.
Similarly, you may ask, what is the Holliday model?
In 1964, Robin Holliday proposed a model that accounted for heteroduplex formation and gene conversion during recombination. It illustrates the critical steps of pairing of homologous duplexes, formation of a heteroduplex, formation of the recombination joint, branch migration and resolution.
What is DSBR?
Two primary models for how homologous recombination repairs double-strand breaks in DNA are the double-strand break repair (DSBR) pathway (sometimes called the double Holliday junction model) and the synthesis-dependent strand annealing (SDSA) pathway.