How is ephedrine used to treat nasal congestion?

Asked By: Cassaundra Zischank | Last Updated: 17th February, 2020
Category: medical health pharmaceutical drugs
4.1/5 (39 Views . 42 Votes)
Used for: A blocked nose (nasal congestion)

Click to see full answer


Beside this, how does ephedrine work for nasal congestion?

Ephedrine is a decongestant and bronchodilator. It works by reducing swelling and constricting blood vessels in the nasal passages and widening the lung airways, allowing you to breathe more easily.

Similarly, how is pseudoephedrine different from ephedrine? Ephedrine is similar in structure to the (semi-synthetic) derivatives amphetamine and methamphetamine. Both ephedrine and pseudoephedrine act as a bronchodilator, but pseudoephedrine has considerably less effect. Both also increase blood pressure, with again pseudoephedrine being considerably less effective.

People also ask, what is Ephedrine used for?

It is commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anesthesia. Ephedrine stimulates the brain, increases the heart rate, increases blood pressure, expands bronchial tubes, increases metabolism, and increases body heat.

What is best for nasal congestion?

Decongestants . These medicines help reduce the swelling in your nasal passages and ease the stuffiness and sinus pressure. They come as nasal sprays, like naphazoline (Privine), oxymetazoline (Afrin, Dristan, Nostrilla, Vicks Sinus Nasal Spray), or phenylephrine (Neo-Synephrine, Sinex, Rhinall).

39 Related Question Answers Found

What is the best decongestant?

Our Top Picks
  • Flonase Allergy Relief Nasal Spray at Amazon.
  • GoodSense Nasal Decongestant at Amazon.
  • Sudafed PE Pressure + Pain + Relief at Amazon.
  • NasalCrom Nasal Allergy Controller at Amazon.
  • Mucinex Sinus-Max Night Time Relief Liquid at Amazon.
  • Breathe Right Clear Nasal Strips at Jet.
  • Afrin Original Nasal Spray at Amazon.

Can you still buy ephedrine?

Due to safety concerns, the Food and Drug Administration (FDA) banned products containing ephedrine in 2004 ( 1 , 19). Some ephedrine-containing medications are still available over the counter, though regulations on the purchase of these products can vary by state.

Can I buy ephedrine over the counter?

Ephedrine is available over-the-counter (OTC) as an oral medication in combination with the expectorant guaifenesin, and comes in the form of tablets, caplets, or syrup. It is not a replacement for prescription asthma treatments.

Is it OK to take pseudoephedrine every day?

Sudafed Congestion
Adults and children 12 years and older: Take two tablets every four to six hours. Do not take more than eight tablets every 24 hours.

How long does it take for ephedrine to work?


Ephedrine
Clinical data
Onset of action IV (seconds), IM (10 min to 20 min), by mouth (15 min to 60 min)
Elimination half-life 3 h to 6 h
Duration of action IV/IM (60 min), by mouth (2 h to 4 h)
Excretion 22% to 99% (urine)

Is Ephedrine a vasopressor?

BACKGROUND: Historically, ephedrine has been the vasopressor of choice for treatment of most cases of hypotension in obstetric patients. However, the choice of vasopressor in the parturient receiving a beta-adrenergic agent for tocolysis has not been evaluated extensively.

How does ephedrine work?

Ephedrine directly stimulates alpha and beta-adrenergic receptors and increases the release of norepinephrine. Its actions include relaxation of bronchioles, increased heart rate and contractility, and increased blood pressure. It also causes blood vessels in the nasal passages to shrink (vasoconstrict).

Is Ephedrine a vasodilator?

Direct- and indirect-acting sympathomimetic action: Ephedrine stimulates alpha- and beta-adrenergic receptors. Vasodilation results from its effect on beta2-adrenergic receptors; vasoconstriction results from its alpha-adrenergic effects.

Can u smoke ephedrine?

Ephedrine was reported to be more effective than amphetamine (p = 0.046). Subjects reported similar changes in feeling of enjoyment of smoking. Active drug produced a statistically significant drop in the actual amount of tobacco smoked in heavy smokers (p = 0.028), but not in light smokers.

What drugs contain ephedrine?


Product(s) containing ephedrine:
  • ephedrine systemic.
  • ephedrine nasal.
  • aminophylline/amobarbital/ephedrine systemic.
  • aminophylline/ephedrine/guaifenesin/phenobarbital systemic.
  • aminophylline/ephedrine/phenobarbital/potassium iodide systemic.

Does ephedrine give you energy?

Ephedrine and How It Works
Ephedrine pills are stimulants that raise the metabolic rate of the user's body. This increases fat loss. Basically, ephedrine increases the energy expended by your body, most of which is from your body fat.

Why do athletes take ephedrine?

Because ephedrine is a sympathomimetic and a central nervous system stimulant, it is commonly used as an energy enhancer. Ma huang-containing products are marketed and used to improve aerobic performance and endurance, reduce fatigue, increase alertness, improve reaction time, and even increase strength.

Can a doctor prescribe ephedrine?

Some weight-loss supplements containing ephedra, ephedrine, or caffeine are available without a prescription (over the counter). It is important to talk to your doctor if you are taking or are considering taking an over-the-counter weight-loss supplement.

How much ephedrine is safe?

Ephedrine is also used as for asthma and supplement for athletes and dieters. Doses of less than 20 milligrams per day are generally considered safe. Most dieters and athletes take 50 to 150 milligrams daily, split into several doses. Its half-life is 3 to 6 hours, which requires up to 3 doses per day.

How do you make ephedrine?


But to make ephedrine, the chemical benzaldehyde is added to the mix; the yeast ferments the benzaldehyde to produce an intermediate product called PAC, which is extracted using organic solvents, and then the PAC is converted into ephedrine in a second catalytic reaction which also requires the use of solvents.

What are the dangers of ephedrine?

Ephedra can cause a quickened heartbeat and elevated blood pressure. Side effects include heart palpitations, nausea, and vomiting. More than 800 dangerous reactions have been reported with use of the herb. These include heart attacks, strokes, seizures, and sudden deaths.

What are the effects of ephedrine?

Common side effects of Ephedrine usually occur with larger doses and include:
  • nervousness,
  • anxiety,
  • dizziness,
  • spinning sensation (vertigo),
  • headache,
  • nausea,
  • loss of appetite,
  • trouble sleeping (insomnia),