How effective is PrEP 2019?

Asked By: Tenesor Gandia | Last Updated: 11th June, 2020
Category: medical health cold and flu
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According to data analysis from the iPrEx study that found PrEP to be effective: For people who take 7 PrEP pills per week, their estimated level of protection is 99%. For people who take 4 PrEP pills per week, their estimated level of protection is 96%.

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In respect to this, how long before PrEP is effective?

Scientists do not yet have an answer on how long it takes PrEP to become fully effective after you start taking it. Some studies suggest that if you take PrEP every day, it reaches its maximum protection in blood at 20 days, in rectal tissue at about 7 days, and in vaginal tissues at about 20 days.

Furthermore, do you take PrEP forever? It isn't a pill you have to take forever. You get to decide when to start and stop PrEP. Just remember that if you don't take it regularly, you aren't as safe.

Also asked, who is PrEP recommended for?

Pre-exposure prophylaxis (or PrEP) is a way for people who do not have HIV but who are at very high risk of getting HIV to prevent HIV infection by taking a pill every day. The pill (brand name Truvada) contains two medicines (tenofovir and emtricitabine) that are used in combination with other medicines to treat HIV.

How long does PrEP stay in your system after you stop taking it?

Together these findings suggested to the researchers that nearly everyone taking TDF/FTC PrEP will attain protective concentrations of tenofovir after 7 days of dosing and that concentrations will remain protective about a week after a person stops taking TDF/FTC.

26 Related Question Answers Found

What is the success rate of PrEP?

PrEP is 92% effective when used every day. PrEP can range from 44% to 92% effective depending on adherence. When used daily, PrEP has an 8% failure rate. PrEP is highly effective.

Is PrEP effective after 3 days?

How soon does PrEP become effective after you start it? It's estimated that it takes at least seven days for PrEP to reach high levels of protection in the body. When used correctly, Truvada for PrEP provides 92%–99% reduction in HIV risk for HIV-negative individuals who take the pills every day as directed.

How effective is PrEP after 5 days?

Results. Twenty-one HIV-uninfected adults participated in Cell-PrEP. The inferred HIV risk reduction, based on PBMC TFV-DP concentration, reached 99% (95% confidence interval [CI], 69%–100%) after 5 daily doses, and remained >90% for 7 days after stopping drug from steady-state conditions.

Can I infect someone while on PEP?

Yes, you can have sex while taking PEP. Still, some guys choose to take a break. It's important to avoid additional exposure to HIV while taking PEP.

Is PrEP effective after 4 days?


Regardless of their findings that PrEP remained quite effective for days after stopping, the researchers still advise starting PrEP about a week before the first possible exposure to HIV and staying on Truvada for four weeks after the last potential exposure.

What happens if I miss a day of PrEP?

If you do miss a dose, don't panic. Take the pill as soon as you remember, unless it is already almost time to take the next dose (in that case, do not take a double dose). Contact your provider if you notice that you are missing doses on a regular basis (and especially if you miss more than 1 or 2 doses a week).

What does PrEP do to your body?

Pre-exposure prophylaxis (PrEP) is an HIV prevention strategy where HIV-negative individuals take anti-HIV medications before coming into contact with HIV to reduce their risk of becoming infected. The medications work to prevent HIV from establishing infection inside the body.

What happens if you accidentally take PrEP twice in one day?

Don't double the dose to catch up. Taking two doses at once could increase your risk of serious side effects. If you think you've accidentally taken two or more doses in one day, call your doctor. They may recommend treatment for any symptoms you may be having, or treatment to prevent side effects from occurring.

Is PrEP safe long term?

They are generally easy to take. Possible long-term side effects include loss of bone mineral density and kidney damage. Some people worry that people taking PrEP might think they are totally protected. They might be less careful about their sexual behavior.

How do I get PrEP for free?


You may be able to receive TRUVADA for PrEP free of charge if you qualify for the Medication Assistance Program. Gilead Advancing Access can help you determine if you are qualified for this program, or help you find alternative coverage options if you are not.

What is the difference between Truvada and Descovy?

The difference between Truvada and Descovy is in the form of tenofovir contained in each product. Descovy contains a newer form of tenofovir called tenofovir alafenamide (TAF) and Truvada contains the original form of tenofovir as tenofovir disoproxil fumarate (TDF).

Should I take PEP if I'm on PrEP?

Is PEP recommended if I am on PrEP? PEP stands for post-exposure prophylaxis and involves taking a combination of three HIV meds for one month. Taking a double-dose of PrEP (if you still have some left) is a good idea as the earlier PEP is started the better it works.

Is PrEP more effective than pep?

PEP – Injection Drug Use Transmission. There are insufficient data about PEP's effectiveness to prevent HIV infections from nonsterile injection drug use. For persons who inject drugs and experience many exposures, PrEP is likely to be a better prevention strategy than PEP.

Can pep be taken for 7 days?

PEP usually isn't given more than 72 hours (3 days) after exposure as studies show it is unlikely to be effective. However, if you are unable to access PEP within the 72 hours, even if it has been up to 5-7 days since the exposure occurred, it is still worth seeking medical advice to see what your options are.

Can I take PrEP instead of pep?


PEP, like PrEP, works by preventing the HIV virus from reproducing itself, but PEP only works if it is taken within 72 hours of exposure. If you think you may have been exposed to HIV you should consider getting PEP as soon as possible. Unlike PrEP, PEP is not intended for prolonged use.

How do I ask my doctor for PrEP?

  1. Be clear. Tell your provider early on that you're interested in PrEP and would like to discuss whether it makes sense for you to use it.
  2. Be forthcoming. In order to help you make the most informed decision possible, you should be forthcoming with your provider about your health and wellness.
  3. Ask questions.
  4. Take notes.

Can you take PrEP after 72 hours?

PEP, or post-exposure prophylaxis, is a short course of HIV medicines taken very soon after a possible exposure to HIV to prevent the virus from taking hold in your body. You must start it within 72 hours after you were exposed to HIV, or it won't work. Every hour counts.