How does angiotensin II affect the kidneys?
In this regard, what are the effects of angiotensin II?
Angiotensin II has effects on: Blood vessels – it increases blood pressure by causing constriction (narrowing) of the blood vessels. Nerves: it increases the sensation of thirst, the desire for salt, encourages the release of other hormones that are involved in fluid retention.
Keeping this in view, can ARBs cause kidney damage?
Adverse effects — Renin-angiotensin system (RAS) inhibition can be associated with a variety of adverse effects. With respect to progression of the renal disease, ACE inhibitors and ARBs can cause a decline in renal function and a rise in serum potassium that typically occur one to two weeks after the onset of therapy.
The intrarenal effects of angiotensin II restore GFR back to normal within one to two weeks, by which time circulating plasma angiotensin II levels are no longer elevated. In contrast to its effects on GFR, angiotensin II has minimal effects on renal blood flow after stenosis.