How did Andy's wife die on NYPD Blue?
Similarly one may ask, what episode does Sylvia die on NYPD Blue?
"NYPD Blue" A Death in the Family (TV Episode 1996) - IMDb.
Similarly, you may ask, what happened to Theo's mom on NYPD Blue?
Theo's mom Sylvia Costas-Sipowicz (as played by Sharon Lawrence) also died tragically; she was shot and killed at the end of Season 6. Her final words to husband Andy were, “Take care of the baby.” The revival is being shepherded by Matt Olmstead and Nick Wootton, both of whom worked on the original NYPD Blue.
His father taught him lessons about being a policeman until Andy Jr. was killed when he intervened in a robbery/rape, and one of the perpetrators shot him. His death sent his father into a tailspin that nearly destroyed his life. After his death, Andy Jr.