How are Holliday junctions resolved?
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Likewise, people ask, how are Holliday junctions formed?
Holliday junction, cross-shaped structure that forms during the process of genetic recombination, when two double-stranded DNA molecules become separated into four strands in order to exchange segments of genetic information.
Additionally, what is strand invasion? Strand invasion. Definition: The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA.
Likewise, people ask, what can the Holliday model help explain?
In 1964, Robin Holliday proposed a model that accounted for heteroduplex formation and gene conversion during recombination. It illustrates the critical steps of pairing of homologous duplexes, formation of a heteroduplex, formation of the recombination joint, branch migration and resolution.
Why does homologous recombination occur?
Homologous Recombination Homologous recombination is a type of genetic recombination that occurs during meiosis (the formation of egg and sperm cells). Paired chromosomes from the male and female parent align so that similar DNA sequences from the paired chromosomes cross over each other.