Does terbutaline affect the baby?

Asked By: Andrej Saget | Last Updated: 6th June, 2020
Category: medical health lung and respiratory health
4.2/5 (55 Views . 40 Votes)
Terbutaline can cause a temporary increase in the baby's heart rate and blood sugar levels. These side effects usually aren't serious and are easy to treat after delivery if they occur. There are concerns about long term use of this drug because the incidence of danger to the baby increases.

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Also asked, is terbutaline safe for baby?

Terbutaline is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Terbutaline is not safe to use in a pregnant woman to prevent premature labor.

Also, what are the side effects of terbutaline? Brand names Brethine, Bricanyl, Brethaire are no longer available in the U.S. Common side effects of terbutaline sulfate injection include:

  • tremor,
  • nervousness,
  • dizziness,
  • headache,
  • drowsiness,
  • palpitations,
  • rapid heart rate,
  • shortness of breath,

Thereof, can terbutaline cause birth defects?

Terbutaline, a β2-adrenoceptor agonist, is used off-label for long-term management of preterm labor; such use is associated with increased risk of neurodevelopmental disorders, including autism spectrum disorders.

How is terbutaline used in pregnancy?

Terbutaline is a medication used to delay preterm labor. It is in a class of drugs called betamimetics, which help prevent and slow contractions of the uterus. Terbutaline is primarily used when doctors need to delay birth for several hours or days in order to allow the child to mature more before being born.

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How fast does terbutaline work?

Terbutaline is used as a fast-acting bronchodilator (often used as a short-term asthma treatment) and as a tocolytic to delay premature labor. The inhaled form of terbutaline starts working within 15 minutes and can last up to 6 hours.

Why is terbutaline banned?

The terbutaline has been kept in the category of banned drugs by WADA because it increases muscle strength.

How many times can terbutaline be given?

Terbutaline comes as a tablet to take by mouth. The tablets are usually taken three times a day, once every six hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

How long can terbutaline delay labor?

Terbutaline can be effective when labor needs to be delayed for 24 to 48 hours. But the medicine usually does not completely stop contractions. Nor has it been shown to lower risks for the premature baby.

What are two contraindications for the administration of terbutaline during labor?


Contraindications / Precautions. Terbutaline sulfate is contraindicated in patients known to be hypersensitive to sympathomimetic amines or any component of this drug product. Immediate hypersensitivity reactions and exacerbations of acute bronchospasm have been reported after terbutaline administration.

What class of drug is terbutaline?

Terbutaline is a member of a class of drugs called beta adrenergic receptor agonists (stimulators) that is used for treating asthma and other diseases of the airways. Other drugs in the same class of drugs include albuterol (Proventil), metaproterenol (Alupent), pirbuterol (Maxair), and salmeterol (Serevent).

Does terbutaline cross placenta?

Terbutaline crossed the placenta rapidly, and fetal plasma levels up to 55% of the maternal plasma levels were found. The conclusion is that this form of administration of terbutaline does not seem to have any negative short-term influences on the fetal carbohydrate metabolism.

What causes prematurity?

Pregnancy-related factors associated with premature birth include:
  • poor nutrition before and during pregnancy.
  • smoking, using illegal drugs, or drinking too much alcohol during pregnancy.
  • certain infections, such as urinary tract and amniotic membrane infections.
  • premature birth in a previous pregnancy.
  • an abnormal uterus.

What pregnancy category is terbutaline?

Terbutaline is in a class of drugs called betamimetics. They help prevent and slow contractions of the uterus. It may help delay birth for several hours or days. During that period, doctors can administer other drugs to help ensure the baby is born as healthy as possible.

Why does terbutaline cause tachycardia?


The tachycardia after the terbutaline infusion has been suggested to be caused by the direct effects on heart rather than systemic effects e.g. decreased blood pressure [38].

Does terbutaline increase heart rate?

Heart rate and blood pressure warning: In rare cases, terbutaline may increase your heart rate and blood pressure. If you have a heart issue, talk to your doctor before starting this drug. Seizures warning: Rarely, this drug can cause seizures.

Is Bromhexine safe in pregnancy?

According to current experience, expectorants and mucolytic agents such as acetyl cysteine, ambroxol, and bromhexine may be used during pregnancy without a recognizable risk of a teratogenic effect.

Can terbutaline cause fetal tachycardia?

Increased fetal heart rate and neonatal hypoglycemia may occur as a result of maternal administration (1-3). Most common maternal adverse effects of terbutaline are headache, nausea, tachycardia and palpitations (1).

What is betamethasone used for in pregnancy?

Antenatal betamethasone is primarily used to speed up lung development in preterm fetuses. It stimulates the synthesis and release of surfactant (2), which lubricates the lungs, allowing the air sacs to slide against one another without sticking when the infant breathes.

Is terbutaline contraindicated with asthma?

Boxed Warning, Contraindication to Be Added to Asthma Drug's Label. Terbutaline is approved to prevent and treat bronchospasm associated with asthma, bronchitis and emphysema, but the drug also has been used off-label for obstetric purposes, including treating preterm labor and uterine hyperstimulation.

Is nifedipine safe during pregnancy?

Nifedipine is an effective drug to treat severe hypertension in pregnancy and preterm labour. Because it is given in a tablet or capsule by mouth, it is easier to use than intravenous drugs. The described side effects of nifedipine to the pregnant woman and her infant appear minimal.