Can allopurinol cause itchy skin?

Asked By: Walburga Korten | Last Updated: 20th June, 2020
Category: medical health pharmaceutical drugs
4.9/5 (57 Views . 43 Votes)
Allopurinol can cause a severe allergic reaction. Symptoms can include: itchy hives (raised bumps on your skin) red or purple-colored spots on your skin.

Click to see full answer


Also know, can allopurinol cause skin rash?

The most frequent adverse reaction to ZYLOPRIM (allopurinol) is skin rash. Skin reactions can be severe and sometimes fatal. Therefore, treatment with ZYLOPRIM (allopurinol) should be discontinued immediately if a rash develops (see WARNINGS).

Also, what are the side effects of taking allopurinol? Serious Side Effects of Allopurinol

  • Fever, sore throat, and headache with a severe blistering, peeling and red skin rash.
  • Any sign of skin rash, no matter how mild.
  • Nausea, upper stomach pain, itching, loss of appetite, weight loss, dark urine, clay-colored stools, jaundice.
  • Pain or bleeding when urinating.

Consequently, how long does it take for allopurinol to get out of your system?

Peak levels of allopurinol are reached within 1.5 hours and 4.5 hours for its active metabolite. Allopurinol may be taken once daily. Normal serum uric acid levels are normally achieved within one to three weeks. It may take two to six weeks before allopurinol effectively reduces gout attacks.

Can taking allopurinol cause weight gain?

Shortness of breath, a big weight gain, or swelling in the arms or legs. Chest pain or pressure. Liver problems have happened with this drug. Sometimes, liver problems have not gone back to normal after this drug was stopped.

39 Related Question Answers Found

Can I stop taking allopurinol?

Do not stop taking allopurinol suddenly unless you have a skin rash or allergic reaction. Speak to your doctor or nurse before stopping. Stopping allopurinol quickly can cause a flare up and make your gout worse.

What can I take instead of allopurinol?

Febuxostat, like allopurinol, is a xanthine oxidase inhibitor that can lower urate levels in patients with gout and thus prevent acute attacks. It has become the usual first alternative for allopurinol-intolerant patients with gout.

Which is better colchicine or allopurinol?

Colchicine is used for acute flare ups of gout to act as an anti-inflammatory by reducing swelling and pain. Allopurinol is an antihyperuricemic which prevents the production of uric acid. Allopurinol is used after an initial flare up and controls chronic gout.

Can you be allergic to allopurinol?

Allopurinol has been associated with severe cutaneous adverse reactions (SCAR), including drug reaction with eosinophilia and systemic symptoms (DRESS), toxic epidermal necrolysis, Stevens–Johnson syndrome and allopurinol hypersensitivity syndrome (AHS).

Can allopurinol cause joint pain?


Allopurinol is used to prevent or lower high uric acid levels in the blood. A high uric acid level can cause gout or gouty arthritis (joint pain and inflammation).

Can allopurinol cause neuropathy?

A patient experienced an axonomyelinic peripheral neuropathy during a long-term allopurinol treatment. The symptoms and signs regressed after drug withdrawal, and the nerve conduction velocities and distal latencies improved. The incidence of allopurinol-induced peripheral neuropathy is very low.

Is allopurinol an Nsaid?

NSAIDs are the most commonly used drugs in acute gout. Over the long term, gout is treated by decreasing tissue stores of uric acid with the xanthine oxidase inhibitors allopurinol or febuxostat or with the uricosuric agent probenecid.

What medications can cause skin rashes?

Almost any drug can cause a rash. But antibiotics (especially penicillins and sulfa drugs), NSAIDs, and anti-seizure drugs are the most common drugs to cause a rash. Read on to learn more about the different kinds of drug rashes and how to manage them.

What does allopurinol do to your body?

Allopurinol reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones. Allopurinol is used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment.

Should I take allopurinol in the morning or at night?


Allopurinol is usually taken once daily. However, if your dose is more than 300 mg, your doctor may advise you to take your medicine twice a day. Then, it should be taken morning and night, after breakfast and dinner.

How long should you take allopurinol?

Remember, allopurinol should be taken every day to prevent a gout attack. It can take 2-3 months to become fully effective. It does not have any effect during a gout attack, although you should continue to take it regularly every day even if this happens.

Is allopurinol bad for your kidneys?

Allopurinol Safe Even With Chronic Kidney Disease. Allopurinol is a safe and effective therapy for lowering urate levels in gout, even in patients with creatinine clearances (CrCL) < 30 mL/min. High doses of allopurinol are rarely needed to achieve acceptable urate levels in patients with chronic kidney disease.

How do you flush uric acid out of your body?

Apple Cider Vinegar: Mix one teaspoon of organic apple cider vinegar to a glass of water and drink this every day. Apple cider vinegar acts like a natural cleanser and detoxifier. It contains malic acid which helps in breaking down and removing uric acid from the body.

Can allopurinol raise blood pressure?

Hyperuricemia has been shown to raise blood pressure (BP) in normotensive rats, and this rise is attenuated by urate-lowering drugs. In 1 study, both allopurinol (a xanthine oxidase inhibitor that reduces the formation of uric acid) and probenecid (a uricosuric drug) were studied.

Can allopurinol cause hair loss?


A gout medication that may cause hair loss is: allopurinol (Zyloprim). It has already been noted that vitamin A in excessive doses over a period of time can cause hair loss. It just happens that in some women, they help stop hair loss, while in others they cause hair thinning.

Is allopurinol hard on kidneys?

Allopurinol does not increase chronic kidney disease risk in gout patients. Hyperuricemia, or high serum urate levels in the blood, can lead to CKD, but clinicians have been cautious about using allopurinol in these patients because of potential adverse events.

What is allopurinol 100mg used for?

Uses. Allopurinol is used to treat gout and certain types of kidney stones. It is also used to prevent increased uric acid levels in patients receiving cancer chemotherapy. These patients can have increased uric acid levels due to release of uric acid from the dying cancer cells.